BellaSeno and Charité – Universitätsmedizin Berlin Collaborate Under BMBF-Funded SyMBoD Consortium

BellaSeno and Charité – Universitätsmedizin Berlin Collaborate Under BMBF-Funded SyMBoD Consortium

Press releases may be edited for formatting or style | March 24, 2020 3D Printing
Leipzig, Germany, March 24, 2020 - BellaSeno GmbH, a company developing absorbable scaffolds using additive manufacturing technologies, today announced a collaboration with Charité – Universitätsmedizin Berlin under the recently established SyMBoD consortium. Under the agreement, BellaSeno will design and manufacture personalized, 3D-printed, absorbable implants suitable for the treatment of diabetes patients with bone defects. The goal is to restore blood supply and facilitate the regeneration of persistent bone defects that do not heal otherwise. The consortium is an interdisciplinary project covering innovative digital technology based on systems medicine and precise, reproducible additive manufacturing. Within the consortium, BellaSeno is fully responsible for ISO 13485-compliant, medical-grade scaffold manufacturing.

"Current research suggests that 3D-printed scaffolds, which have been optimized mechanically and biologically, can improve bone regeneration," said Dr. Navid Khani, Head of R&D of BellaSeno. "Our custom-made, high-speed additive manufacturing platform is very precise, generates highly reproducible structures and has been certified according to ISO 13485 standard. We are therefore very well positioned to produce state-of-the-art, medical-grade scaffolds for a variety of applications. This is the first project underlining our manufacturing capabilities for external industry and academic partners."

"We have selected BellaSeno because of the team´s unique expertise in additive manufacturing of porous structures with extremely small features as required for our intended application," said Dr. Su Ping Patrina Poh of Charité's Julius Wolff Institute (JWI). "This strategic inclusion of BellaSeno is also driven by the fact that, to our knowledge, they are the only company within Germany with the capability to perform the entire additive design and manufacturing process chain with ISO13485 certified processes, which is highly aligned with our intention of clinical translation in the future.

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BellaSeno is producing 3D-printed absorbable implants in very high-resolution lattice-based structures using melt-extrusion technology. While numerous companies can manufacture porous structures using 3D-printing technologies, it is extremely challenging to reproducibly generate structures if the required unit-cell size is less than 3 mm. Using its custom-built Yasham additive manufacturing platform, BellaSeno can reproducibly and routinely manufacture scaffolds with unit cell sizes down to about 1 mm.

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