dismiss

In less than 1 week! Our Clean Sweep Auction on August 2nd at 9:30AM EDT goes LIVE

DOTmed Home MRI Oncology Ultrasound Molecular Imaging X-Ray Cardiology Health IT Business Affairs
News Home Parts & Service Operating Room CT Women's Health Proton Therapy Endoscopy HTMs Mobile Imaging
SEARCH
当前地点:
>
> This Story


注册记数器 to rate this News Story
Forward Printable StoryPrint Comment

 

Molecular Imaging Homepage

Researchers develop new PET/CT technique to more accurately diagnose cardiac sarcoidosis Can spot the disease in other organs as well

PET scans could improve dementia diagnosis in two-thirds of patients 'A swift and accurate diagnosis has a huge impact on access to Alzheimer's treatments.'

Siemens gets FDA nod for its Biograph Horizon Flow edition PET/CT Marketed as a "cost-competitive" system

German researchers develop new PET tracer for detecting blood clots Could help inform smarter use of anticoagulants

SPECT and SPECT/CT Product Showcase Check out some of the latest innovations from the leading manufacturers

The Future of nuclear medicine: Driving value in expanded clinical use Kees Wesdorp and Kirill Shalyaev examine the ways scientific breakthroughs translate into lives — and money — saved

New optimism regarding the supply of Moly-99 The workhorse SPECT isotope will not run out any time soon: Experts

PET/CT, PET/MR and PET Product Showcase A quick look at all the leading modalities in the market

How fast will the U.S. market get access to Gallium-68? The nuclear medicine world is preparing for the introduction of Ga-68 tracers

Purchasing insights: Molecular imaging modalities will grow in the coming years What to look for when your facility is investing in new systems

Gadolinium may become
a thing of the past

Researchers develop metal-free MR contrast agent for high-risk patients

Lauren Dubinsky , Senior Reporter
Researchers at MIT and the University of Nebraska have developed a metal-free MR contrast agent that could be a safer option for high-risk patients.

"This is an entirely organic, metal-free MRI contrast agent that would allow cancer researchers to start to think about how to image tumors in a dynamic way over long periods of time," Jeremiah Johnson, professor at MIT, said in a statement.

Story Continues Below Advertisement

CT, MRI, NM, SPECT/CT, PET & PET/CT service, refurbished systems and parts

Accelerate your ROI with our Black Diamond Certified refurbished systems. One year warranty - ISO 13485 Certified - FDA registered - Over 65k parts in inventory DOTmed Certified



The most common MR contrast agents are based on the metal gadolinium, which cannot be used in patients with certain types of kidney problems.

The agent has also been under scrutiny lately due to research that showed it is retained in the brain. As a result, there has been an increasing interest in developing alternatives.

Scientists have tried to create non-metal agents such as organic radicals, which are compounds with unpaired electrons. They are usually broken down in the bloodstream within minutes and they don't produce as much MR contrast as metal agents.

In a paper recently published in ACS Central Science, Johnson and his colleagues described how they were able to manipulate the radicals into nitroxide brush-arm star polymer nanoparticles that can last in the bloodstream for up to 20 hours.

They demonstrated that it's a long enough time span to accumulate in a tumor in mice and that the nanoparticles are not harmful to mice even at very high doses.

Johnson envisions that these nanoparticles can be designed to carry drugs as well as an MR contrast agent. That would allow clinicians to monitor a tumor in the long term to determine if the drug is working.

He is also working with researchers at MIT's Koch Institute for Integrative Cancer Research to attach the contrast agent particles to antibodies that would help target specific cells for imaging and potentially, drug delivery.

Molecular Imaging Homepage


You Must Be Logged In To Post A Comment

做广告
提升您的品牌知名度
拍卖+私人销售
获得最好的价格
买设备/配件
找到最低价格
每日新闻
阅读最新信息
目录
浏览所有的DOTmed用户
DOTmed上的伦理
查看我们的伦理计划
金子分开供营商节目
接收PH要求
金子服务经销商节目
接收请求
提供保健服务者
查看所有的HCP(简称医疗保健提供商)的工具
工作/训练
查找/申请工作
Parts Hunter +EasyPay
获取配件报价
最近证明
查看最近通过认证的用户
最近额定
查看最近通过认证的用户
出租中央
租用设备优惠
卖设备/配件
得到最划算
服务技术员论坛
查找帮助和建议
简单的征求建议书
获取设备报价
真正商业展览
查找对设备的服务
对这个站点的通入和用途是受期限和条件我们支配 法律公告 & 保密性通知
物产和业主对 DOTmed.com,公司 Copyright ©2001-2017 DOTmed.com, Inc.
版权所有