DOTmed Home MRI Oncology Ultrasound Molecular Imaging X-Ray Cardiology Health IT Business Affairs
News Home Parts & Service Operating Room CT Women's Health Proton Therapy Endoscopy HTMs Mobile Imaging
SEARCH
当前地点:
>
> This Story


注册记数器 to rate this News Story
Forward Printable StoryPrint Comment

 

 

MRI Homepage

Brigham and Women's Hospital pioneers intraoperative imaging with AMIGO Suite Insights from one of the pioneering teams in intraoperative MR

New cardiac MR imaging technique eliminates breath holds and shortens exam time May have applications for imaging cancer patients too

New ultrasound imaging technique better detects prostate cancer SHI may yield a better value than MR for evaluating prostate

Don Listwin Silicon Valley leader joins innovator in cerebrovascular imaging to revolutionize stroke care

MR reveals immune cell role in traumatic brain injury repair Repair damaged blood vessels of the meninges

Researchers develop unique 7T MR head coil for better imaging 'Tic-Tac-Toe' shows promise in neurological diseases

Intraoperative MR is improving outcomes at Nicklaus Children's in Miami Insights from pediatric neurosurgeon, Dr. Travis Tierney

Avante partners with EMS for CT and MR expertise Combining to offer a more robust portfolio to healthcare providers

CMS eases up on MR requirements for patients with implants Extends coverage to patients with pacemakers, ICDs, CRT-Ps, and CRT-Ds

NVIDIA aims to bring AI insights to existing global fleet of imaging systems With Project Clara, older scanners may gain remote access to latest capabilities

Gadolinium nanoparticles biomineralized
in transferrin proteins

Image courtesy of Nano Letters

Researchers create tumor-targeting MR contrast agent using human proteins

Lauren Dubinsky , Senior Reporter
Because gadolinium-based contrast agents have been shown to be retained in the brain, the industry has been on a quest to find a viable alternative.

A human protein-based tumor-targeting MR contrast agent that can be easily cleared by the body may be what they’ve been looking for.

Story Continues Below Advertisement

The (#1 Resource) for Medical Imaging and Peripherals. Call 1-949-273-8000

As a Master Distributor for major brands Barco, Philips, and Sony, we offer custom imaging solutions. With our renowned OEM Solutions and Service/Repair Center, Ampronix is a one-stop shop for HD Medical LCD Displays--Printers--Recorders--4K Cameras



A team led by Gang Han, associate professor at the University of Massachusetts Medical School, designed this new contrast agent and found that it holds promise for clinical application. He told HCB News that to the best of his knowledge, it’s the first human protein-based MR contrast.

Sugar has also been investigated as a potential alternative to gadolinium. Research published in Tomography in January and Radiology last month demonstrated that sugar can be used as an MR contrast agent to detect tumors.

Han’s team focused on proteins because they are naturally-occurring nanomaterials. The protein-bound nanoparticle Abraxane, for example, can be used to treat metastatic breast cancer, and protein scaffolds can improve the effectiveness of contrast agents.

In a paper published last month in Nano Letters, Han and his colleagues explained how they created a protein-based contrast agent. They used human transferrin (Tf) proteins to mimic the natural process of forming special nanoparticles called gadolinium biomineralized human Tf protein-based nanoparticles (Gd@TfNP).

The Gd@TfNPs preserve the functions of Tf very well, have superior chemical and physical properties and are brighter, compared to the gadolinium-based agents currently in use, said Han.

Because of that, Gd@TfNPs can be used as systemically clearable contrast agents for detecting early-stage tumors with MR. They can also be used to optimize drug dose and evaluate clinical results.

“This patent of this technology has been submitted,” said Han. “There is already some industry interest since this paper was published.”

MRI Homepage


You Must Be Logged In To Post A Comment

做广告
提升您的品牌知名度
拍卖+私人销售
获得最好的价格
买设备/配件
找到最低价格
每日新闻
阅读最新信息
目录
浏览所有的DOTmed用户
DOTmed上的伦理
查看我们的伦理计划
金子分开供营商节目
接收PH要求
金子服务经销商节目
接收请求
提供保健服务者
查看所有的HCP(简称医疗保健提供商)的工具
工作/训练
查找/申请工作
Parts Hunter +EasyPay
获取配件报价
最近证明
查看最近通过认证的用户
最近额定
查看最近通过认证的用户
出租中央
租用设备优惠
卖设备/配件
得到最划算
服务技术员论坛
查找帮助和建议
简单的征求建议书
获取设备报价
真正商业展览
查找对设备的服务
对这个站点的通入和用途是受期限和条件我们支配 法律公告 & 保密性通知
物产和业主对 DOTmed.com,公司 Copyright ©2001-2018 DOTmed.com, Inc.
版权所有